![]() This method of presenting information is a substitution of concepts, when laboratory findings are issued as clinical results. On almost every supplement site, you can purchase preparations made from powder or turmeric extract and find information on the pharmacological effect of curcumin on dozens of diseases. It is worth noting that laboratory studies with curcumin have greatly increased interest in it all over the world, and this was especially evident in the segment of dietary supplements. This low bioavailability prevents curcumin from showing its therapeutic potential while taking as powder or extract. Unfortunately, these encouraging initial findings were not supported in human clinical trials due to the very low bioavailability of curcumin, which averaged no more than 0.1%. įurthermore, in laboratory conditions curcumin has demonstrated multiple pharmacological properties, including antioxidant, anti-inflammatory, anticarcinogenic, cardioprotective, hepatoprotective, antidepressant, immune-strengthening, and many others Curcumin chelates the toxicity of metals, helps to normalize the content of GSH, SOD, CAT, protects hemoglobin from oxidation, interacts with membrane components and prevents lipid peroxidation inside microsomes, erythrocytes and brain homogenates. Curcumin has been shown ability to cross the blood-brain barrier, to provide protective effects against oxidative damage, to reduce ROS. Laboratory studies have shown that curcumin is a therapeutically useful tool for preventing or correcting the negative effects of mercury on the body. ![]() Ĭurcumin is one of the most widely tested natural compounds. Ĭurcumin is the main curcuminoid found in turmeric root.
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